Diabetic drugs can reduce Alzheimer’s disease risk

18 August 2021, 3:38 pm
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People taking certain drugs to lower blood sugar for type 2 diabetes were found to have less amyloid in the brain, which is a biomarker of Alzheimer’s disease.

The findings of the study were published in the journal ‘American Academy of Neurology’.

The study also found people taking these drugs, called dipeptidyl peptidase-4 inhibitors, showed slower cognitive decline than people in the other two groups.

In people with type 2 diabetes, the body no longer efficiently uses insulin to control blood sugar.

Dipeptidyl peptidase-4 inhibitors, also known as gliptins, can be prescribed when other diabetes drugs do not work. They help control blood sugar when combined with diet and exercise.

“People with diabetes have been shown to have a higher risk of Alzheimer’s disease, possibly due to high blood sugar levels, which have been linked to the buildup of amyloid-beta in the brain,” said study author Phil Hyu Lee, MD, PhD, of Yonsei University College of Medicine in Seoul, South Korea.

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